An embryonic structure that is derived from the inner cell mass and lies above the hypoblast and gives rise to the three primary germ layers. [ MP:0003886 ]
Term information
- EHDAA:42
- NCIT:C34164
- UMLS:C1516906 (ncithesaurus:Epiblast)
- EMAPA:16050
- EHDAA:75
- EHDAA2:0000444
pheno_slim, early_development
The epiblast cells (appearing on day 8 of human embryonic development) make up a columnar epithelium with dense microvilli on the apical surface. During gastrulation, the epiblast cells undergo epithelial-to-mesenchymal transition and delaminate to become the loose mesenchyme of the primitive streak. The epiblast is present in postimplantation mouse embryos between E5.5-E7.5.