Neural crest cells (NCCs) originating in the anterior part of the developing embryo and residing between the mid-diencephalon and the forming hindbrain; cranial NCCs migrate dorsolaterally to form the craniofacial mesenchyme that differentiates into various craniofacial cartilages and bones, cranial neurons, glia, and connective tissues of the face; these cells enter the pharyngeal pouches and arches where they give rise to thymic cells, bones of the middle ear and jaw (mandible), and the odontoblasts of the tooth primordia; like their counterparts in the trunk, cranial NCCs also contribute to the developing peripheral nervous system, along with the pigmented cell (i.e. melanocyte) lineage. [ http://www.informatics.jax.org/accession/anna ]
Synonyms: CNC cranial NCC population cephalic neural crest head NCC population
Term information
- VHOG:0000063
- Wikipedia:Cranial_neural_crest
- EMAPA:16091
- AAO:0010580
- XAO:0001001
- EFO:0003645
- ZFA:0001194
- TAO:0001194
- EHDAA2:0004420
uberon_slim, efo_slim, vertebrate_core
Neural crest that is part of the head.[TAO]
Anterior most portion of the neural crest. Migrates in three highly conserved streams: mandibular, hyoid and branchial.[AAO]
We conclude this section by listing some of the many synapomorphies of craniates, including (1) the neural crest (...).[well established][VHOG]
Term relations
- embryonic tissue
- cellular anatomical structure
- part of some neural crest
- has part some migratory cranial neural crest cell