Somites are spheres of epithelial cells that form sequentially along the anterior-posterior axis of the embryo through mesenchymal to epithelial transition of the presomitic mesoderm. [ http://dx.doi.org/10.1111/j.1439-0426.2012.01987.x http://en.wikipedia.org/wiki/Somite ]
Term information
- ZFA:0000155
- MESH:D019170
- AAO:0010569
- EHDAA:366
- TAO:0000155
- EHDAA2:0003436
- Wikipedia:Somite
- AEO:0001015
- FMA:85522
- GAID:1306
- MAT:0000068
- UMLS:C0376449 (ncithesaurus:Somite)
- EHDAA:699
- VHOG:0000191
- BTO:0001558
- NCIT:C34302
- EMAPA:31169
- XAO:0000058
- MIAA:0000068
uberon_slim, pheno_slim, vertebrate_core
Undifferentiated mesodermal components of early trunk or tail segments or metameres, derived from paraxial mesoderm; forms myotomes, sclerotomes and perhaps dermatomes. Kimmel et al, 1995.[TAO]
Post-cranial axial segments which form sclerotome and dermomyotome.[AAO]
relationship loss: develops_from paraxial mesenchyme (TAO:0000942)[TAO]
relationship type change: part_of paraxial mesoderm (AAO:0010568) CHANGED TO: develops_from paraxial mesoderm (UBERON:0003077)[AAO]
relationship type change: OBO_REL:part_of trunk (TAO:0001115) CHANGED TO: develops_from trunk (UBERON:0002100)[TAO]
(...) cephalocordates and craniates belong to a group known as Somitichordata. Somitichordate synapomorphies include (1) somites (...) (reference 1); The idea that the last common ancestor of bilaterian animals (Urbilateria) was segmented has been raised recently on evidence coming from comparative molecular embryology (reference 2).[well established][VHOG]
When the somite becomes segmented from the segmental plate, it is composed of an epithelial sac enclosing mesenchymal somitocoel cells. Thereafter the somite differentiates into two parts, the ventro-medial mesenchymal sclerotome and the dorso-lateral epithelial dermomyotome. This change in the epithelial somite depends on surrounding tissue [PMID:15906248]
currently classified as an epithelial vesicle, consistent with EHDAA2 and https://github.com/obophenotype/uberon/wiki/The-neural-crest. Consider making 'somitic mesoderm' a separate term and correlate with regionalization processes. Consider moving ZFA term to 'trunk somite' as it is part of the trunk
Term relations
- epithelial vesicle
- developing anatomical structure
- develops from some presomitic mesoderm
- only in taxon some Chordata