A myogenic muscular circulatory organ found in the vertebrate cardiovascular system composed of chambers of cardiac muscle. It is the primary circulatory organ. [ http://en.wikipedia.org/wiki/Heart http://orcid.org/0000-0002-6601-2165 ]
Synonyms: vertebrate heart chambered heart
Term information
- MESH:D006321
- EHDAA2:0000738
- AAO:0010210
- ZFA:0000114
- CALOHA:TS-0445
- XAO:0000064
- GAID:174
- FMA:7088
- UMLS:C0018787 (ncithesaurus:Heart)
- TAO:0000114
- MAT:0000036
- EV:0100018
- EHDAA:420
- MA:0000072
- MIAA:0000036
- EMAPA:16105
- SCTID:302509004
- OpenCyc:Mx4rvVjvDpwpEbGdrcN5Y29ycA
- Wikipedia:Heart
- VHOG:0000276
- EFO:0000815
- NCIT:C12727
- BTO:0000562
- BILA:0000020
- galen:Heart
uberon_slim, efo_slim, pheno_slim, vertebrate_core, organ_slim, major_organ, human_reference_atlas
http://purl.obolibrary.org/obo/NCBITaxon_6239
http://purl.obolibrary.org/obo/NCBITaxon_7227
Blood pumping organ composed of four chambers: sinus venosus, atrium, cardiac ventricle and bulbus arteriosus.[TAO]
Part of the circulatory system responsible for pumping blood; composed of three chambers--two atria and one ventricle.[AAO]
relationship type change: differentiates_from lateral plate mesoderm (AAO:0010574) CHANGED TO: develops_from lateral plate mesoderm (UBERON:0003081)[AAO]
As noted, the hearts of birds and mammals have four chambers that arises from the two chambers (atrium and ventricle) of the fish heart.[well established][VHOG]
Taxon notes:" the ascidian tube-like heart lacks chambers....The ascidian heart is formed after metamorphosis as a simple tube-like structure with a single-layered myoepithelium that is continuous with a single-layered pericar- dial wall. It lacks chambers and endocardium.... The innovation of the chambered heart was a key event in vertebrate evolution, because the chambered heart generates one-way blood flow with high pressure, a critical requirement for the efficient blood supply of large-body vertebrates... all extant vertebrates have hearts with two or more chambers (Moorman and Christoffels 2003)" DOI:10.1101/gad.1485706
Term relations
- structure with developmental contribution from neural crest
- mesoderm-derived structure
- primary circulatory organ
- thoracic segment organ
- contributes to morphology of some cardiovascular system
- part of some heart plus pericardium
- develops from some heart tube
- only in taxon some Vertebrata
- has part some cardiac chamber
- epicardium
- heart elastic tissue
- wall of heart
- cardiac muscle tissue
- mesentery of heart
- heart vasculature
- cardiac endothelial cell
- cardiac glial cell
- cardiac skeleton
- cardiac chamber
- outflow tract
- cardiac mesenchyme
- bulbus cordis
- heart endothelium
- coronary vessel
- heart layer
- fibroblast of cardiac tissue
- cardiac septum
- atrioventricular region