The clusters of hormone-producing cells that are scattered throughout the pancreas. [ http://www.informatics.jax.org/searches/AMA.cgi?id=MA:0000127 MP:0005215 MESH:A03.734.414 ]
Synonyms: pancreatic islet pancreatic insula
Term information
- NCIT:C12608
- EMAPA:32927
- UMLS:C0022131 (ncithesaurus:Islet_of_Langerhans)
- VHOG:0000646
- EV:0100130
- MIAA:0000076
- BTO:0000991
- GAID:324
- FMA:16016
- MA:0000127
- MAT:0000076
- XAO:0000159
- EFO:0000856
- MESH:D007515
- Wikipedia:Islets_of_Langerhans
- CALOHA:TS-0741
- AAO:0010406
uberon_slim, efo_slim, pheno_slim, human_reference_atlas
Anatomical structure which consists of glands developed from pancreatic ducts in the larvae and secrete insulin.[AAO]
Mammals, birds, reptiles and amphibians have a pancreas with similar histology and mode of development, while in some fish, the islet cells are segregated as Brockmann bodies.[well established][VHOG]
A primitive exocrine pancreas can be found in holocephalan cartilaginous fish; a pancreatic duct directly ending in the gut lumen is connected to a glandular structure made of exocrine cells and associated with cell islets, which comprises three different hormone-producing cell types: insulin, somatostatin and glucagon (Yui and Fujita, 1986)