The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell. [ GOC:mtg_signaling_feb11 GOC:go_curators ]

This is just here as a test because I lose it

Term information

Subsets

goslim_chembl, goslim_metagenomics, goslim_plant, goslim_candida

comment

Note that signal transduction is defined broadly to include a ligand interacting with a receptor, downstream signaling steps and a response being triggered. A change in form of the signal in every step is not necessary. Note that in many cases the end of this process is regulation of the initiation of transcription. Note that specific transcription factors may be annotated to this term, but core/general transcription machinery such as RNA polymerase should not.

hasAlternativeId

GO:0023033

GO:0023045

GO:0023015

GO:0023014

GO:0023016

hasOBONamespace

biological_process

has narrow synonym

signal transduction by protein phosphorylation

signal transduction by conformational transition

signal transduction by cis-phosphorylation

signaling cascade

signalling cascade

signal transduction by trans-phosphorylation

has related synonym

signalling pathway

signaling pathway

id

GO:0007165