A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. [ http://www.ncbi.nlm.nih.gov/pubmed/14701881 GOC:dph ]
Synonyms: mesenchymal cell differentiation from epithelial cell epithelial-mesenchymal transition EMT
Term information
Term relations
- cell differentiation and has input some epithelial cell and results in acquisition of features of some mesenchymal cell