Animals exhibit variations in the form, structure, composition or arrangement of any of the various filamentous elements that form the internal framework of cells, compared to control. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles. [ http://www.wormbase.org/get?name=WBPerson2021 http://www.wormbase.org/get?name=WBPerson557 http://amigo.geneontology.org/amigo/term/GO:0005856 ]