A flexible rod-shaped body found in embryos of all chordates. It is composed of cells derived from the mesoderm and defines the primitive axis of the embryo. In some chordates, it persists throughout life as the main axial support of the body, while in most vertebrates it becomes the nucleus pulposus of the intervertebral disc. The notochord is found ventral to the neural tube. [ https://github.com/obophenotype/uberon/issues/25 https://www.worldcat.org/search?q=bn%3A0815318960 https://github.com/obophenotype/uberon/issues/271 http://en.wikipedia.org/wiki/Notochord http://tolweb.org/Chordata/2499 ]
Synonyms: notocord embryonic notocord
Term information
- null:http://evolution.berkeley.edu/evolibrary/images/history/notochords.jpg
- EHDAA:6021
- GAID:1311
- VHOG:0000199
- BTO:0001768
- EHDAA:1241
- Wikipedia:Notochord
- MAT:0000281
- EHDAA2:0001277
- NCIT:C12463
- EV:0100002
- EMAPA:16191
- FMA:85521
- UMLS:C0028439 (ncithesaurus:Notochord)
- AAO:0000327
- VSAO:0000032
- MESH:D009672
- ZFA:0000135
- CALOHA:TS-0690
- XAO:0000055
- TAO:0000135
- SCTID:308820002
uberon_slim, pheno_slim, vertebrate_core
Rod-like principal supportive element of the embryo and larva, present in the midline just ventral to the neural tube, and differentiating during the segmentation period to form large vacuolated epithelial cells and a surrounding a sheath of fibrous and elastic layers. Layering of the sheath may differ in structure, thickness and development among groups; in cypriniforms there are actually three very thin layers to the sheath. A functional, well developed notochord is present throughout life in certain basal fish groups but not in cypriniforms. Kimmel et al, 1995.[TAO]
Slender rod of fibrous connective tissue surrounding a core of fluid-filled cells of mesodermal origin; it lies above the gut and directly beneath the spinal cord. The notochord is present during early development and in a few cases it is retained through life; however, usually the notochord is replaced by the vertebral column.[AAO]
Avascular multi-tissue structure composed of large vacuolated epithelial cells (chordablasts) and perichordal fibrous tissue.[VSAO]
relationship type change: differentiates_from mesoderm (AAO:0000304) CHANGED TO: develops_from mesoderm (UBERON:0000926)[AAO]
(...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (3) a stiff, longitudinal rod of turgid cells along the dorsal part of the body that is called a notochord (...).[well established][VHOG]
In between vertebra the notochord becomes the nucleus pulposus, under it degenerates, and at anterior end in some species its tissue merges with some of the cranial bones.. Some organisms retain a post-embryonic notochord.
The notochord appears early in embryogeny and plays an important role in promoting or organizing the embryonic development of nearby structures. In most adult chordates the notochord disappears or becomes highly modified. In some non-vertebrate chordates and fishes the notochord persists as a laterally flexible but incompressible skeletal rod that prevents telescopic collapse of the body during swimming[TOLWEB]
Term relations
- multi-tissue structure
- ectoderm-derived structure
- part of some axial skeletal system
- produces some sonic hedgehog protein
- ventral to some neural tube
- develops from some chordamesoderm
- existence starts during some embryo stage
- develops from some notochordal plate
- dorsal to some digestive tract
- only in taxon some Chordata