An organ of sight that includes the camera-type eyeball and supporting structures such as the lacrimal apparatus, the conjunctiva, the eyelid. [ https://orcid.org/0000-0002-6601-2165 http://amigo.geneontology.org/amigo/term/GO:0043010 ]
Synonyms: regio orbitalis
Term information
- UMLS:C0015392 (ncithesaurus:Eye)
- NCIT:C12401
- TAO:0000107
- EMAPA:16198
- FMA:54448
- UMLS:C1280202 (BIRNLEX:1169)
- EHDAA:936
- OpenCyc:Mx8Ngx4rwKSh9pwpEbGdrcN5Y29ycB4rvVil5pwpEbGdrcN5Y29ycB4rvViTvpwpEbGdrcN5Y29ycA
- MA:0000261
- AAO:0010340
- VHOG:0000275
- BTO:0004688
- XAO:0000179
- EHDAA2:0000484
- UMLS:C0015392 (BIRNLEX:1169)
- BIRNLEX:1169
- SCTID:181143004
- ZFA:0000107
uberon_slim, pheno_slim, vertebrate_core
The eye of the adult lamprey is remarkably similar to our own, and it possesses numerous features (including the expression of opsin genes) that are very similar to those of the eyes of jawed vertebrates. The lamprey's camera-like eye has a lens, an iris and extra-ocular muscles (five of them, unlike the eyes of jawed vertebrates, which have six), although it lacks intra-ocular muscles. Its retina also has a structure very similar to that of the retinas of other vertebrates, with three nuclear layers comprised of the cell bodies of photoreceptors and bipolar, horizontal, amacrine and ganglion cells. The southern hemisphere lamprey, Geotria australis, possesses five morphological classes of retinal photoreceptor and five classes of opsin, each of which is closely related to the opsins of jawed vertebrates. Given these similarities, we reach the inescapable conclusion that the last common ancestor of jawless and jawed vertebrates already possessed an eye that was comparable to that of extant lampreys and gnathostomes. Accordingly, a vertebrate camera-like eye must have been present by the time that lampreys and gnathostomes diverged, around 500 Mya.[well established][VHOG]
FMA distinguishes Eye (subdivision of face) which has its parts an Eyeball (organ), as well as other structures, and the orbit of skull. MA includes eyelid, conjunctiva and lacrimal apparatus as part of MA:eye - consistent with FMA - so we can infer that MA:eye is more like FMA:eye than FMA:eyeball. For other AOs this distinction is less meaningful - e.g. ZFA has no eyelid; XAO has no eyelid, but it has conjuctiva, which is considered part of the xao:eye. GO considers eyelid development part of eye development. See also notes on optic nerve - XAO, AAO and BTO consider this part of the eye. MA considers the eye muscles part of the eye, whereas FMA has a class 'orbital content' for this
camera-type eye plus associated structures
orbital part of face
orbital region
eyes
Term relations
- simple eye
- lateral structure
- ectoderm-derived structure
- structure with developmental contribution from neural crest
- part of some orbital region
- develops from some optic cup
- has part some lens of camera-type eye
- in lateral side of some head
- existence ends during some fully formed stage
- has part some retina