The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome. [ GOC:go_curators ]
Synonyms: protein formation protein translation protein biosynthesis protein anabolism protein biosynthetic process protein synthesis
Term information
goslim_chembl, goslim_metagenomics, goslim_drosophila, goslim_pir, prokaryote_subset, goslim_plant, goslim_candida
Term relations
- biosynthetic process and part of some gene expression and has primary output some protein polypeptide chain
- peptide biosynthetic process
- protein metabolic process
- cellular macromolecule biosynthetic process
- biosynthetic process
- part of some gene expression
- has primary output some protein polypeptide chain
- has part some translational elongation
- starts with some translational initiation
- ends with some translational termination