The simple cuboidal epithelium lining the lumen of kidney collecting ducts. [ http://www.informatics.jax.org/accession/anna MP:0011843 ]
Synonyms: collecting duct of renal tubule epithelium epithelium of renal collecting tubule epithelium of collecting duct of renal tubule
Term information
pheno_slim
In mouse, the mature and differentiated CD epithelium comprises two unique cells types with principal cells responsible for vasopressin-regulated water reabsorption, and intercalated cells regulating acid-base homeostasis; injury to the epithelium is believed to cause epithelial cells to acquire mesenchymal characteristics via epithelial-mesenchymal transition (EMT), a process through which tubular epithelial cells may transform into interstitial fibroblasts and promote renal fibrosis