The interstitial compartment of the kidney, comprising the extravascular intertubular spaces of the renal parenchyma, with their attendant cellular elements and extracellular substances, bounded on all sides by epithelial and vascular basement membranes. [ http://www.ncbi.nlm.nih.gov/pubmed/18575881 http://dx.doi.org/10.1038/ki.1991.49 http://orcid.org/0000-0002-6601-2165 ]
Synonyms: renal stroma renal interstitial tissue interstitial tissue of kidney renal interstitium stroma of kidney
Term information
- MA:0002616
- NCIT:C33459
- SCTID:362210003
- FMA:70983
- EMAPA:28518
pheno_slim, human_reference_atlas
The interstitium is necessarily involved in all intrarenal exchange processes since the reabsorption and secretion of fluid and solutes implicates a transit across the interstitial compartment.
The fibroblasts in the interstitium provide the 'skeleton' of the tissue and maintain the three-dimensional architecture of the tissue.