An anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate[GO]. a microscopic structure in the kidney, which regulates the function of each nephron. The juxtaglomerular apparatus is named for its proximity to the glomerulus: it is found between the vascular pole of the renal corpuscle and the returning distal convoluted tubule of the same nephron. This location is critical to its function in regulating renal blood flow and glomerular filtration rate. The three cellular components of the apparatus are the macula densa, extraglomerular mesangial cells, and juxtaglomerular cells (also known as granular cells)[WP]. [ http://en.wikipedia.org/wiki/Juxtaglomerular_apparatus http://amigo.geneontology.org/amigo/term/GO:0072206 ]
Synonyms: juxtaglomerular complex complexus juxtaglomerularis
Term information
- Wikipedia:Juxtaglomerular_apparatus
- BTO:0005157
- SCTID:362219002
- MA:0002546
- FMA:83599
- GAID:432
- EMAPA:30449
- NCIT:C32891
- UMLS:C0022445 (ncithesaurus:Juxtaglomerular_Apparatus)
- MESH:D007606
uberon_slim, pheno_slim, human_reference_atlas
Term relations
- environment associated with an animal part or small animal
- protein-containing material entity
- cellular anatomical structure
- capable of some regulation of glomerular filtration
- has part some kidney granular cell
- has part some macula densa
- bearer of some maximally connected
- bearer of some mass
- part of some cortex of kidney
- bearer of some 3-D shape
- existence starts during or after some zygote stage
- has part some extraglomerular mesangial cell
- end stage some death stage