The subcommissural organ is a circumventricular organ consisting of ependymal and hypendymal cells which secrete SCO-spondin[WP,partially vetted]. [ http://www.ncbi.nlm.nih.gov/pubmed/9579598 http://en.wikipedia.org/wiki/Subcommissural_organ ]
Term information
- Wikipedia:Subcommissural_organ
- TAO:0000683
- SCTID:369193006
- UMLS:C0038533 (BIRNLEX:1028)
- BIRNLEX:1028
- neuronames:483 (BIRNLEX:1028)
- DHBA:12101
- EMAPA:35828
- HBA:9489
- MESH:D013351
- ZFA:0000683
- FMA:72414
- BTO:0001820
- GAID:794
- BAMS:SCO
- DMBA:16514
- CALOHA:TS-0986
- MA:0002941
uberon_slim, pheno_slim, vertebrate_core
Occurs throughout the vertebartes [PMID:9579598, DOI:10.1002/ar.1091260210]. First appears in hagfish(Olsson). In many species, including the human, it reaches its full development during embryonic life[PMID:9579598]. During the course of phyletic evolution, one notes various changes. Indeed, in lower vertebrates, the SCO presents a greater degree of enzyme activity than the ependyma while in birds the ependyma demonstrates a more intense activity than the SCO[PMID:479574] Sometimes preceded by flexural organ[DOI:10.1007/BF00303086]. Hypendymal cells are rare in non-mammals [PMID:9579598].
Hypendymal cells being part of the subcommissural organ is not axiomatized as it is rare in non-mammals. Consider using GCIs if this axiom needs to be added.
cerebral aqueduct subcommissural organ
dorsal subcommissural organ
organum subcommissurale
corpus subcommissurale
SCO
Term relations
- secretory circumventricular organ
- protein-containing material entity
- part of some Reissner's fiber
- produces some SCO-spondin
- part of some midbrain tectum
- has part some ependymal cell