Cranial nerve fiber tract which is comprised of retinal ganglion cell axons running posterior medially towards the optic chiasm, at which some of the axons cross the midline and after which the structure is termed the optic tract. Transmits visual information from the retina to the brain[ZFA]. [ https://www.worldcat.org/search?q=bn%3A0471888893 https://www.worldcat.org/search?q=bn%3A0471209627 ]
Synonyms: optic II second cranial nerve optic nerve [II] 02 optic nerve nervus opticus nervus opticus [II] cranial II optic II nerve
Term information
- MESH:D009900
- SCTID:180938001
- MA:0001097
- DHBA:15544
- UMLS:C0029130 (ncithesaurus:Optic_Nerve)
- BIRNLEX:1640
- HBA:9307
- TAO:0000435
- BAMS:2n
- EMAPA:17575
- ZFA:0000435
- AAO:0010345
- BAMS:nII
- VHOG:0000543
- neuronames:289 (BIRNLEX:1640)
- MBA:848
- EFO:0004258
- Wikipedia:Optic_nerve
- XAO:0000188
- BAMS:IIn
- CALOHA:TS-0713
- FMA:50863
- EHDAA:6788
- EHDAA2:0001313
- NCIT:C12761
- GAID:831
uberon_slim, efo_slim, pheno_slim, vertebrate_core
Do not classify under 'cranial nerve', as this is not a true nerve - should be classified as evaginated sensory afferent[ISBN:0471888893]
A collection of nerve cells that project visual information from the eyes to the brain. (Source: BioGlossary, www.Biology-Text.com)[TAO]
Fibrous, somatic sensory element covered by a fibrous connective-tissue sheath and is continuous with the layer of nerve cells on the inner surface of the eye.[AAO]
(relaion to eye): MA, XAO, AAO and BTO consider this part of the eye. This is in contrast to GO, FMA, EHDAA2 (FMA has a class 'intra-ocular part of optic nerve' which represents the region of overlap). Relation to brain: part of diencephalon in EHDAA2, ZFA. In NIF, has the optic nerve root as part, which is a feature part of the diencphalon
(...) an essentially similar sequence of events occurs during the embryonic development of the vertebrate eye. The eye initially develops as a single median evagination of the diencephalon that soon bifurcates to form the paired optic vesicles. As each optic vesicle grows towards the body surface, its proximal part narrows as the optic stalk, and its distal part invaginates to form a two-layered optic cup (reference 1); The (optic) stalk persists as the optic nerve (reference 2).[well established][VHOG]
Term relations
- cranial neuron projection bundle and innervates some retina and extends_fibers_into some optic chiasma