An integrin alpha with A domain that is a translation product of the human ITGAM gene or a 1:1 ortholog thereof. They constitute subunits of the integrin alpha-M/beta-2 receptor. This receptor is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is also a receptor for fibrinogen, factor X and ICAM1. [ https://www.uniprot.org/uniprot/P11215 ]
Synonyms: ITGAM cell surface glycoprotein MAC-1 subunit alpha CD11 antigen-like family member B CD11b CR-3 alpha chain leukocyte adhesion receptor MO1 neutrophil adherence receptor
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- granulocyte
- Kupffer cell
- monoblast
- microglial cell
- myeloid suppressor cell
- elicited macrophage
- peritoneal macrophage
- alveolar macrophage
- promonocyte
- CD115-positive monocyte
- CD11b-positive dendritic cell
- CD11b-positive, CD27-positive natural killer cell, mouse
- CD27-high, CD11b-low natural killer cell, mouse
- CD27-low, CD11b-high natural killer cell, mouse
- CD27-high, CD11b-high natural killer cell, mouse
- CD27-low, CD11b-low immature natural killer cell, mouse