cysteine-type endopeptidase activity involved in apoptotic signaling pathway

cysteine-type endopeptidase activity involved in apoptotic signaling pathway

http://purl.obolibrary.org/obo/GO_0097199

Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the apoptotic signaling pathway. [ GOC:mtg_apoptosis http://en.wikipedia.org/wiki/Caspase http://www.ncbi.nlm.nih.gov/pubmed/11717445 ]

Synonyms: cysteine-type endopeptidase activity involved in apoptotic signalling pathway

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Examples of gene products that may be annotated to this term include CASP2, CASP8, CASP9, and CASP10, also called initiator (or apical, or activator) caspases.

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creation date

2011-12-12T01:43:00Z

has narrow synonym

activator caspase activity

apical caspase activity

initiator caspase activity

has obo namespace

molecular_function

GO:0097199