The activity of a gene product that interacts with a receptor to effect a change in the activity of the receptor. Ligands may be produced by the same, or different, cell that expresses the receptor. Ligands may diffuse extracellularly from their point of origin to the receiving cell, or remain attached to an adjacent cell surface (e.g. Notch ligands). [ GOC:pdt GOC:molecular_function_refactoring GOC:kv ]
Synonyms: signaling receptor ligand activity signaling molecule
Term information
goslim_chembl, goslim_generic, goslim_drosophila