A protein complex formed by the association of several methylated Sm proteins with the SMN complex; the latter contains the survival motor neuron (SMN) protein and at least eight additional integral components, including the Gemin2-8 and unrip proteins; additional proteins, including galectin-1 and galectin-3, are also found in the SMN-SM complex. The SMN-Sm complex is involved in spliceosomal snRNP assembly in the cytoplasm. [ http://www.ncbi.nlm.nih.gov/pubmed/11522829 GOC:vw http://www.ncbi.nlm.nih.gov/pubmed/17401408 ]
Term information
Note that this complex is sometimes referred to as the 'SMN complex', but it should not be confused with GO:0032797.