DNA-templated transcription initiation
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The initial step of transcription, consisting of the assembly of the RNA polymerase preinitiation complex (PIC) at a gene promoter, as well as the formation of the first few bonds of the RNA transcript. Transcription initiation includes abortive initiation events, which occur when the first few nucleotides are repeatedly synthesized and then released, and ends when promoter clearance takes place. [ http://www.ncbi.nlm.nih.gov/pubmed/18280161 GOC:jid GOC:txnOH ]
Synonyms: DNA-dependent RNA polymerase complex assembly at promoter DNA-templated transcription, initiation initiation of DNA-dependent transcription DNA-dependent transcription, initiation initiation of transcription, DNA-dependent
Term information
goslim_yeast
Note that promoter clearance is represented as a separate step, not part_of either initiation or elongation.
transcription initiation, DNA-dependent
transcription initiation factor activity