A wide pore channel activity that enables a direct cytoplasmic connection from one cell to an adjacent cell. The gap junction can pass large solutes as well as electrical signals between cells. Gap junctions consist of two gap junction hemi-channels, or connexons, one contributed by each membrane through which the gap junction passes. [ GOC:dgh https://www.worldcat.org/search?q=bn%3A0815340729 GOC:mtg_transport ]
Synonyms: innexin channel activity
Term information
- Reactome:R-HSA-375340 (Connexin 62 mediated neuronal gap junction communication)
- Reactome:R-HSA-190681 (Connexin oligomerization in endoplasmic reticulum membrane)
- Reactome:R-HSA-375330 (Connexin 45/Connexin 36 mediated neuronal gap junction communication)
- Reactome:R-HSA-375342 (Connexin 36 mediated neuronal gap junction communication)
- Reactome:R-HSA-375339 (Pannexin 1/Pannexin2 mediated neuronal gap junction communication)