Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. [ http://www.iuphar-db.org http://en.wikipedia.org/wiki/GPCR GOC:bf ]
Synonyms: GPCR activity G-protein coupled receptor activity receptor activity, G-protein coupled G protein coupled receptor activity G-protein linked receptor activity ligand-dependent GPCR activity G protein linked receptor activity
Term information
- Reactome:R-HSA-114552 (G12/13 activation by PAR)
- Reactome:R-HSA-167408 (The high affinity receptor complex binds to G-protein)
- Reactome:R-HSA-114558 (Gq activation by PAR)
- Wikipedia:GPCR
- Reactome:R-HSA-114552 (Thrombin-activated PARs activate G12/13)
- Reactome:R-HSA-114558 (Thrombin-activated PARs activate Gq)
goslim_chembl
EBV-induced receptor
Epstein-Barr Virus-induced receptor activity
SREB receptor
super conserved receptor expressed in brain receptor activity
RDC1 receptor activity
orphan GPCR activity
Mas proto-oncogene receptor activity
orphan G-protein coupled receptor activity
orphan G protein coupled receptor activity
G-protein coupled receptor activity, unknown ligand