Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain. [ http://merops.sanger.ac.uk/about/glossary.htm#ENDOPEPTIDASE ]
This is just here as a test because I lose it
Term information
database
cross reference
- Reactome:R-HSA-8849797 (Membrane proteases cleave Profilaggrin producing Filaggrin)
- Reactome:R-HSA-5358340 (Autoproteolytic cleavage of Hh precursors)
- Reactome:R-HSA-3928656 (gamma-secretase cleaves EPHB2)
- Reactome:R-HSA-1236970 (Proteasomal clevage of exogenous antigen)
- Reactome:R-HSA-353125 (26S proteosome degrades ODC holoenzyme complex)
- Reactome:R-HSA-9762096 (Ub,pS335,S338,T NFE2L2 is degraded)
- Reactome:R-HSA-174202 (Degradation of multiubiquitinated Securin)
- Reactome:R-HSA-5607731 (26S proteasome processes p-7S-p100:RELB to form p52:RELB)
- Reactome:R-HSA-74730 (Insulin degradation)
- Reactome:R-HSA-5687112 (MAPK6 is degraded by the 26S proteasome)
- Reactome:R-HSA-1504193 (Ubiquitinated DVL is degraded by the proteasome)
- Reactome:R-HSA-5635854 (GLI2,3 are degraded by the proteasome)
- Reactome:R-HSA-9008110 (Proteasome degrades polyubiquitinated RUNX2)
- Reactome:R-HSA-8957265 (26S proteasome degrades TP73 polyubiquitinated by ITCH)
- Reactome:R-HSA-9614271 (Autocleavage of ADGRG6)
- Reactome:R-HSA-8866858 (CFTR F508del is degraded by the 26S proteasome)
- Reactome:R-HSA-174058 (Degradation of multiubiquitinated Cdh1)
- Reactome:R-HSA-264458 (Proteasome mediated degradation of COP1)
- Reactome:R-HSA-8854044 (Proteasome degrades AURKA ubiquitinated by SCF-FBXL7)
- Reactome:R-HSA-5658430 (NF1 is degraded by the proteasome)
- Reactome:R-HSA-9008475 (Proteasome degrades polyubiquitinated RUNX2)
- Reactome:R-HSA-8932355 (26S proteasome degrades Ub-NFE2L2)
- Reactome:R-HSA-180603 (Proteosome-mediated degradation of APOBEC3G)
- Reactome:R-HSA-2213200 (Release of endostatin-like peptides)
- Reactome:R-HSA-5635868 (ub-GLI is degraded by the proteasome)
- Reactome:R-HSA-193682 (gamma-secretase cleaves the p75NTR transmembrane domain)
- Reactome:R-HSA-9010096 (Gamma-secretase cleaves APP(672-770) to APP(672-711) and APP(672-713))
- Reactome:R-HSA-5387392 (processing defective Hh variants are degraded by the proteasome)
- Reactome:R-HSA-5668481 (Protesomal degradation of K48polyUb-TRAF3)
- Reactome:R-HSA-3640874 (Ub-RibC-AXIN is degraded by the proteasome)
- Reactome:R-HSA-68948 (Ubiquitinated Orc1 is degraded by the proteasome)
- Reactome:R-HSA-8939801 (26S proteasome degrades PolyUb-RUNX2)
- Reactome:R-HSA-1234159 (Proteasome proteolyzes ub-HIF-alpha)
- Reactome:R-HSA-8952408 (Polyubiquitinated RUNX3 is degraded by the proteasome)
- Reactome:R-HSA-211715 (Proteasome mediated degradation of PAK-2p34)
- Reactome:R-HSA-209061 (Ubiquitinated and phosphorylated IKBA binds to and is degraded by the proteasome complex)
- Reactome:R-HSA-9604642 (Proteasome degrades ubiquitinated NICD4)
- Reactome:R-HSA-188191 (APC/C:Cdh1-mediated degradation of Skp2)
- Reactome:R-HSA-75825 (Proteasome mediated degradation of Cyclin D1)
- Reactome:R-HSA-4641260 (Ubiquitinated DVL1 is degraded by the proteasome)
- Reactome:R-HSA-69016 (Ubiquitinated Cdc6 is degraded by the proteasome)
- Reactome:R-HSA-983150 (Proteasomal cleavage of substrate)
- Reactome:R-HSA-8852354 (GTSE1 facilitates proteasome-mediated degradation of TP53)
- Reactome:R-HSA-9755303 (26S proteasome degrades HIFalpha)
- Reactome:R-HSA-180573 (Degradation of ubiquitinated CD4)
- Reactome:R-HSA-1251997 (Cleavage of ERBB4m80 by gamma-scretase complex)
- Reactome:R-HSA-9011313 (Proteasome degrades ubiquitinated ROBO3.1)
- Reactome:R-HSA-6784628 (PCSK6,FURIN mediate dissociation of 2 x LPL from GPIHBP1:HSPG:LPL dimer)
- Reactome:R-HSA-5610757 (GLI2 is degraded by the proteasome)
- Reactome:R-HSA-5668520 (26Sproteasome degrades K48polyUb-NIK)
- Reactome:R-HSA-5358460 (HPE SHH variants don't undergo autoproteolytic cleavage)
- Reactome:R-HSA-9009362 (Proteasome degrades PolyUb-RUNX2)
- Reactome:R-HSA-4608855 (PRICKLE1 is degraded by the proteasome)
- Reactome:R-HSA-69600 (Proteolytic degradation of ubiquitinated-Cdc25A)
- Reactome:R-HSA-5607724 (26S proteasome processes K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex to form NF-kB complex)
- Reactome:R-HSA-174105 (Degradation of multiubiquitinated cell cycle proteins)
- Reactome:R-HSA-5610760 (GLI1 is degraded by the proteasome after ubiquitination by ITCH)
- Reactome:R-HSA-2130282 (Degradation of ubiquitinated beta catenin by the proteasome)
- Reactome:R-HSA-5362448 (Hh C-terminal fragments are degraded by the proteasome)
- Reactome:R-HSA-983158 (Trimming of peptides in ER)
- Reactome:R-HSA-187574 (Degradation of ubiquitinated p27/p21 by the 26S proteasome)
- Reactome:R-HSA-1236935 (Proteasomal cleavage of substrate)
- Reactome:R-HSA-1433374 (Processing of SCF isoform 1)
- Reactome:R-HSA-5610758 (GLI1 is degraded by the proteasome after ubiquitination by beta-TrCP)
- Reactome:R-HSA-174255 (Degradation multiubiquitinated Cyclin A)
- Reactome:R-HSA-8866553 (misfolded CFTR is degraded by the 26S proteasome)
- Reactome:R-HSA-5610754 (GLI3 is partially degraded by the proteasome to yield the GLI3 repressor)
- Reactome:R-HSA-6784676 (PCSK5 mediates dissociation of 2 x LPL from GPIHBP1:HSPG:LPL dimer)
- Reactome:R-HSA-8850992 (Proteasome degrades polyubiquitinated PTEN)
- Reactome:R-HSA-8934819 (Cytoplasmic proteases cleave Profilaggrin producing Filaggrin)
- Reactome:R-HSA-9755306 (ub UBXN7 is degraded by the 26S proteasome)
- Reactome:R-HSA-8854071 (Proteasome-mediated degradation of PolyUb-FBXL7)
- Reactome:R-HSA-68825 (Ubiquitinated geminin is degraded by the proteasome)
- MetaCyc:RXN0-5195
- Reactome:R-HSA-450466 (AUF1:mRNA complex is destroyed)
- Reactome:R-HSA-174203 (SCF-mediated degradation of Emi1)
- Reactome:R-HSA-4641256 (Ubiquitinated AXIN is degraded by the proteasome)
- Reactome:R-HSA-5693081 (FURIN cleaves 7K-BACE1 to 7K-BACE1(46-501))
- Reactome:R-HSA-1168640 (Ubiquitinated IkB is degraded)