endocardial cushion to mesenchymal transition involved in heart valve formation

Go to external page http://purl.obolibrary.org/obo/GO_0003199


A transition where an endocardial cushion cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the formation of a cardiac valve. [ GOC:mtg_heart ]

Synonyms: endocardial cushion to mesenchymal transition involved in valve formation