epithelial to mesenchymal transition involved in endocardial cushion formation

Go to external page http://purl.obolibrary.org/obo/GO_0003198


A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the formation of the endocardial cushion. [ GOC:mtg_heart ]