epithelial to mesenchymal transition

Go to external page http://purl.obolibrary.org/obo/GO_0001837


A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. [ GOC:dph http://www.ncbi.nlm.nih.gov/pubmed/14701881 ]

Synonyms: mesenchymal cell differentiation from epithelial cell epithelial-mesenchymal transition EMT