A ribonuclease complex that has 3-prime to 5-prime processive and distributive hydrolytic exoribonuclease activity and endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured. [ http://www.ncbi.nlm.nih.gov/pubmed/20531386 http://www.ncbi.nlm.nih.gov/pubmed/17174896 http://www.ncbi.nlm.nih.gov/pubmed/26726035 ]
Synonyms: nuclear exosome (ribonuclease complex) eukaryotic exosome multienzyme ribonuclease complex nuclear exosome multienzyme ribonuclease complex