mitotic spindle assembly checkpoint override

mitotic spindle assembly checkpoint override

http://purl.obolibrary.org/obo/FYPO_0004537

A cellular process phenotype in which a mitotic cell cycle arrest that normally occurs in response to mitotic cell cycle spindle assembly checkpoint signaling does not occur. As a result, the septation initiation network (SIN) signaling pathway is activated despite activation of the mitotic spindle assembly checkpoint (SAC). Normally, under conditions that activate the SAC, SIN activation is inhibited and the cell cycle arrests in anaphase. In this phenotype, premature SIN activation leads to premature cytokinesis and the formation of cut cells. [ https://www.pombase.org/gene/mah https://www.pombase.org/gene/vw http://www.ncbi.nlm.nih.gov/pubmed/11952833 ]

Synonyms: mitotic SAC override mitotic cell cycle spindle assembly checkpoint override SIN activation in presence of active mitotic SAC septation initiation signaling activation in presence of active mitotic spindle assembly checkpoint abolished response to mitotic cell cycle spindle assembly checkpoint signaling

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This is just here as a test because I lose it

Term information

created by

midori

creation date

2015-04-02T14:10:40Z

has obo namespace

fission_yeast_phenotype

FYPO:0004537

Term relations

Subclass of:

abnormal response to mitotic cell cycle spindle assembly checkpoint signaling
abolished response to mitotic cell cycle checkpoint signaling
has_output some cut
has part some (
    lacking processual parts and
    during some single-celled organism vegetative growth phase and
    characteristic of some response to mitotic spindle checkpoint signaling and
    has modifier some abnormal)