abolished response to mitotic cell cycle checkpoint signaling
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A cellular process phenotype in which a mitotic cell cycle arrest that normally occurs in response to cell cycle checkpoint signaling does not occur. Abolished arrest may result from a problem with detection of conditions that normally trigger a checkpoint, transduction of the checkpoint signal, or the response to the checkpoint signal. [ https://www.pombase.org/gene/mah ]
Synonyms: cell cycle arrest resulting from mitotic cell cycle checkpoint activation abolished
Term information
May indicate that a cell cycle checkpoint is not activated under conditions that normally trigger checkpoint signaling and subsequent cell cycle arrest.
Term relations
- abolished cellular process
- abnormal response to biotic stimulus
- abnormal response to mitotic cell cycle checkpoint signaling
- has part some (
lacking processual parts and
during some single-celled organism vegetative growth phase and
characteristic of some response to mitotic cell cycle checkpoint signaling and
has modifier some abnormal) - has_output some premature cell cycle phase transition