An immature myeloid leukocyte of heterogeneous phenotype found particularly in cancer and sepsis patients that is capable of suppressing activity of T cells in ex vivo assays. This cell type is CD45-positive, CD11b-positive. [ http://www.ncbi.nlm.nih.gov/pubmed/17016559 GOC:ana http://purl.obolibrary.org/obo/go/references/0000031 http://www.ncbi.nlm.nih.gov/pubmed/17016554 GOC:add http://www.ncbi.nlm.nih.gov/pubmed/16168663 ]
Term information
blood_and_immune_upper_slim
Markers: Mouse: CD11b+GR1+CD31+; Human: CD34+ CD33+CD15-CD13+. (According to some reports in humans these cells are iNOS+ARG1+IL13+IFNg+); location: In cancerous tissue; in the blood and lymphoid organs in sepsis.
Term relations
- myeloid leukocyte and bearer of some immature and has plasma membrane part some receptor-type tyrosine-protein phosphatase C and has plasma membrane part some integrin alpha-M and capable of some negative regulation of immune response
- myeloid leukocyte
- protein-containing material entity
- has plasma membrane part some receptor-type tyrosine-protein phosphatase C
- has part some receptor-type tyrosine-protein phosphatase C
- capable of some negative regulation of immune response
- has part some integrin alpha-M
- has plasma membrane part some integrin alpha-M
- bearer of some immature