CD8-positive, alpha-beta cytotoxic T cell
Go to external page http://purl.obolibrary.org/obo/CL_0000794
A CD8-positive, alpha-beta T cell that is capable of killing target cells in an antigen specific manner with the phenotype perforin-positive and granzyme B-positive. [ GOC:add http://purl.obolibrary.org/obo/go/references/0000031 https://www.worldcat.org/search?q=bn%3A0781735149 GOC:pam GOC:tfm ]
Synonyms: CD8-positive, alpha-beta cytotoxic T lymphocyte CD8-positive, alpha-beta cytotoxic T-lymphocyte CD8-positive, alpha-beta cytotoxic T-cell
Term information
- CALOHA:TS-0190
- FMA:70573
human_reference_atlas
Note that while T cells of this subset are loosely referred to 'cytotoxic T cells,' as many other T cell types, including CD4-positive, alpha-beta T cells and gamma-delta T cells exhibit cytotoxicity in vitro and in vivo.
cytotoxic T cell
killer T-cell
cytotoxic T lymphocyte
killer T-lymphocyte
killer T lymphocyte
cytotoxic T-cell
cytotoxic T-lymphocyte
killer T cell
Term relations
- CD8-positive, alpha-beta T cell and has part some perforin-1 and has part some granzyme B and capable of some T cell mediated cytotoxicity and capable of some granzyme B localization to T cell secretory granule and output of some T cell differentiation