A dendritic cell of the myeloid lineage. [ http://www.ncbi.nlm.nih.gov/pubmed/9521319 GOC:add http://www.ncbi.nlm.nih.gov/pubmed/10449155 http://www.ncbi.nlm.nih.gov/pubmed/17332250 ]
Synonyms: CD11c+CD123- DC mDC
Term information
human_reference_atlas
These cells are CD1a-negative, CD1b-positive, CD11a-positive, CD11c-positive, CD13-positive, CD14-negative, CD20-negative, CD21-negative, CD33-positive, CD40-negative, CD50-positive, CD54-positive, CD58-positive, CD68-negative, CD80-negative, CD83-negative, CD85j-positive, CD86-positive, CD89-negative, CD95-positive, CD120a-negative, CD120b-positive, CD123-negative, CD178-negative, CD206-negative, CD207-negative, CD209-negative, and TNF-alpha-negative. Upon TLR stimulation, they are capable of producing high levels of TNF-alpha, IL-6, CXCL8 (IL-8).
Term relations
- conventional dendritic cell and lacks_plasma_membrane_part some interleukin-3 receptor class 2 alpha chain and develops from some myeloid cell
- myeloid leukocyte
- conventional dendritic cell
- lacks_plasma_membrane_part some interleukin-3 receptor class 2 alpha chain
- develops from some myeloid cell