Any of the immature or mature forms of a granular leukocyte with a nucleus that usually has two lobes connected by one or more slender threads of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and which can be stained by the dye eosin. Eosinophils are CD9-positive, CD191-positive, and CD193-positive. [ GOC:amm https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2626675 GOC:dsd GOC:tfm http://www.ncbi.nlm.nih.gov/pubmed/1662676 https://www.worldcat.org/search?q=bn%3A0721601464 GOC:add http://www.ncbi.nlm.nih.gov/pubmed/10914487 ]
Synonyms: eosinophilic leukocyte eosinocyte eosinophilic leucocyte eosinophilic granulocyte
Term information
- BTO:0000399
- MESH:D004804
- CALOHA:TS-0279
- FMA:62861
blood_and_immune_upper_slim, human_reference_atlas
Eosinophils are also CD14-negative, CD32-positive, CD44-positive, CD48-positive, CD69-positive, CD192-negative, MBP1-positive, MBP2-positive, TLR2-negative, TLR4-negative, and lineage-negative (B220, CD2, CD14, CD19, CD56, CD71, CD117, CD123, CD235a (glycophorin A), and TER119). The cytokines IL-3, IL-5, and GM-CSF are involved in their development and differentiation. Usually considered CD16-negative, CD16 is observed on eosinophilic metamyelocyte.
Term relations
- granulocyte and has plasma membrane part some C-C chemokine receptor type 1 and has plasma membrane part some C-C chemokine receptor type 3 and has plasma membrane part some CD44 molecule and has plasma membrane part some CD69 molecule and has plasma membrane part some CD9 molecule
- granulocyte
- has part some C-C chemokine receptor type 3
- has part some C-C chemokine receptor type 1
- has part some CD44 molecule
- has part some CD9 molecule
- has part some CD69 molecule