A tissue-resident macrophage found in the alveoli of the lungs. Ingests small inhaled particles resulting in degradation and presentation of the antigen to immunocompetent cells. Markers include F4/80-positive, CD11b-/low, CD11c-positive, CD68-positive, sialoadhesin-positive, dectin-1-positive, MR-positive, CX3CR1-negative. [ MESH:D016676 GOC:ana GOC:dsd GOC:tfm http://purl.obolibrary.org/obo/go/references/0000031 ]
Synonyms: dust cell
Term information
- BTO:0000802
- CALOHA:TS-0030
- FMA:83023
human_reference_atlas
Markers: Mouse: F4/80mid, CD11b-/low, CD11c+, CD68+, sialoadhesin+, dectin-1+, MR+, CX3CR1-.
Term relations
- tissue-resident macrophage and lacks_plasma_membrane_part some CX3C chemokine receptor 1 and located in some alveolus of lung and has plasma membrane part some integrin alpha-X and has plasma membrane part some C-type lectin domain family 7 member A and has plasma membrane part some adhesion G protein-coupled receptor E1 and has plasma membrane part some sialoadhesin and has plasma membrane part some macrosialin and has plasma membrane part some macrophage mannose receptor 1 and capable of some antigen processing and presentation and has low plasma membrane amount some integrin alpha-M
- tissue-resident macrophage
- protein-containing material entity
- lung macrophage
- has part some C-type lectin domain family 7 member A
- has part some adhesion G protein-coupled receptor E1
- has part some integrin alpha-M
- has part some sialoadhesin
- has part some macrosialin
- has part some integrin alpha-X
- has part some macrophage mannose receptor 1