A cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. These cells are lineage negative (CD3-negative, CD19-negative, CD34-negative, and CD56-negative). [ GOC:add https://www.worldcat.org/search?q=bn%3A0781735149 ]
Term information
- MESH:D003713
- BTO:0002042
- FMA:83036
- CALOHA:TS-0194
general_cell_types_upper_slim, human_reference_atlas
Term relations
- leukocyte and has part some MHC class II protein complex and lacks_plasma_membrane_part some CD19 molecule and lacks_plasma_membrane_part some CD34 molecule and lacks_plasma_membrane_part some CD3 epsilon and lacks_plasma_membrane_part some neural cell adhesion molecule 1 and lacks_plasma_membrane_part some membrane-spanning 4-domains subfamily A member 1 and bearer of some mononucleate and capable of some cytokine production and capable of some antigen processing and presentation of peptide or polysaccharide antigen via MHC class II and capable of some antigen processing and presentation and capable of some regulation of T cell differentiation
- mononuclear cell
- professional antigen presenting cell
- protein-containing material entity
- has part some MHC class II protein complex
- lacks_plasma_membrane_part some CD19 molecule
- lacks_plasma_membrane_part some CD3 epsilon
- lacks_plasma_membrane_part some neural cell adhesion molecule 1
- lacks_plasma_membrane_part some CD34 molecule
- capable of some cytokine production
- capable of some regulation of T cell differentiation
- lacks_plasma_membrane_part some membrane-spanning 4-domains subfamily A member 1