Epithelial progenitor cell of the lung. Club cells are dome-shaped with short microvilli but no cilia. They function to protect the bronchiolar epithelium. Club cells also multiply and differentiate into ciliated cells to regenerate the bronchiolar epithelium. [ http://dx.doi.org/10.1183/09031936.00146609 http://www.ncbi.nlm.nih.gov/pubmed/7905712 GOC:tfm DOI:https://doi.org/10.1378/chest.12-2762 http://www.ncbi.nlm.nih.gov/pubmed/28128362 ]
A non-mucous, epithelial secretory cell that is part of the tracheobronchial tree. A club cell has short microvilli but no cilia. A club cell is able to multiply and differentiate into ciliated cells to regenerate the bronchiolar epithelium and it also protects the tracheobronchial epithelium. [ http://dx.doi.org/10.1378/chest.12-2762 http://www.ncbi.nlm.nih.gov/pubmed/7905712 http://www.ncbi.nlm.nih.gov/pubmed/29874100 http://dx.doi.org/10.1183/09031936.00146609 http://www.ncbi.nlm.nih.gov/pubmed/28128362 GOC:tfm ]
Synonyms: bronchiolar non-ciliated cell club cell of bronchiole Clara cell
Term information
Term relations
- bronchial epithelial cell and bearer of some domed and has plasma membrane part some microvillus and capable of some secretion by cell and capable of some surfactant homeostasis
- bronchial epithelial cell
- progenitor cell
- surfactant secreting cell
- has plasma membrane part some microvillus
- has part some microvillus
- bearer of some domed