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microglial cell

Go to external page http://purl.obolibrary.org/obo/CL_0000129

Synonyms: hortega cells microgliocyte microglia brain-resident macrophage

This is just here as a test because I lose it

Term information

Subsets

human_reference_atlas

plural term
microglia [ doi:10.1038/s41598-020-66092-9 ]

comment

Unlike macroglial cells, microglial cells arise from hematopoietic stem cells in the yolk sac during early embryogenesis that populate the central nervous system. They derive from embryonic mesoderm and are not from neuroectoderm where glioblast develops from. Markers: Mouse: CD11b+, F4/80+, CD68+. They represent ~12% of the cells in the CNS, but they are not uniformly distributed within the CNS. A normal adult mouse brain has approximately 3.5x10e6 microglia. Microglia are also reportedly CD3-negative, CD4-positive, CD8-negative, CD11b-positive, CD11c-high, CD14-negative, CD19-negative, CD45-low, CD56-negative, CD163-negative, CD200R-positive, CD281-positive, CD282-positive, CD283-positive, CD284-positive, CD285-positive, CD286-positive, CD287-positive, CD288-positive, CD289-positive, Gr1-negative, nestin-positive, and PU.1-positive.

has broad synonym

brain macrophage

has related synonym

MF.microglia.CNS

microglia

present in taxon

http://purl.obolibrary.org/obo/NCBITaxon_9606