A oligopotent progenitor cell committed to the lymphoid lineage. [ http://www.ncbi.nlm.nih.gov/pubmed/10407577 GOC:dsd GOC:add http://www.ncbi.nlm.nih.gov/pubmed/16551251 GOC:tfm ]
Synonyms: CLP common lymphocyte precursor common lymphoid precursor common lymphocyte progenitor
Term information
human_reference_atlas
CLP are CD7-positive, CD10-positive, CD19-negative, CD34-positive, CD45RA-positive, CD79a-negative, CD127-positive, AA4.1-positive, RAG-negative, Sca-1-low, sIgM-negative, sIgD-negative, TdT-negative, Vpre-B-negative, and pre-BCR-negative. Expression of transcription factors include E2A-positive, EBF-positive, Ikaros-negative, PU.1-negative, and Pax5-negative.
committed lymphopoietic stem cell
lymphopoietic stem cell
ELP
early lymphocyte progenitor
lymphoid stem cell
Term relations
- hematopoietic oligopotent progenitor cell
- progenitor cell
- capable of some lymphocyte differentiation