A myeloid progenitor cell committed to the monocyte lineage. This cell is CD11b-positive, has basophilic cytoplasm, euchromatin, and the presence of a nucleolus. [ http://en.wikipedia.org/wiki/Monoblast http://www.copewithcytokines.de GOC:add http://www.ncbi.nlm.nih.gov/pubmed/1104740 ]
Term information
- FMA:83553
- CALOHA:TS-1195
Morphology: mononuclear cell, diameter 12-20 _M, non-granular, N/C ratio 3/1 - 4/1; markers: CD11b (shared with many other myeloid cells); location: Adult: bone marrow; fetal: liver, Yolk Sac; role or process: hematopoiesis, monocyte development; lineage: hematopoietic, myeloid.
CFU-M
colony forming unit macrophage
colony forming unit monocyte
monocyte stem cell
Term relations
- monopoietic cell and has part some basophilic cytoplasm and has part some euchromatin and has part some nucleolus and has plasma membrane part some integrin alpha-M and capable of some monocyte differentiation
- monopoietic cell
- myeloid cell
- protein-containing material entity
- mesoderm-derived structure
- has part some nucleolus
- has part some euchromatin
- has part some integrin alpha-M
- has plasma membrane part some integrin alpha-M
- has part some basophilic cytoplasm
- develops from some macrophage dendritic cell progenitor