A morphinane alkaloid that is a highly potent opiate analgesic psychoactive drug. Morphine acts directly on the central nervous system (CNS) to relieve pain but has a high potential for addiction, with tolerance and both physical and psychological dependence developing rapidly. Morphine is the most abundant opiate found in Papaver somniferum (the opium poppy).
Synonyms: 17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol Morphine
Term information
- KNApSAcK:C00001889
- PMID:27815868 (Europe PMC)
- Beilstein:93704 (Beilstein)
- PMID:20071451 (Europe PMC)
- DrugBank:DB00295
- PMID:23988259 (Europe PMC)
- PDBeChem:MOI
- CAS:57-27-2 (ChemIDplus)
- PMID:23555556 (Europe PMC)
- PMID:12593758 (Europe PMC)
- PMID:23325235 (Europe PMC)
- PMID:27866460 (Europe PMC)
- PMID:24096538 (Europe PMC)
- MetaCyc:MORPHINE
- KEGG:D08233
- PMID:23292329 (Europe PMC)
- Wikipedia:Morphine
- VSDB:2982
- KEGG:C01516
- PMID:27735107 (Europe PMC)
- PMID:17667569 (Europe PMC)
- PMID:29368335 (Europe PMC)
- PMID:23927484 (Europe PMC)
- PMID:17171884 (Europe PMC)
- PMID:19371311 (Europe PMC)
- PMID:15019787 (Europe PMC)
- PMID:9231550 (Europe PMC)
- CAS:57-27-2 (KEGG COMPOUND)
- CAS:57-27-2 (NIST Chemistry WebBook)
- PMID:21061062 (Europe PMC)
- Drug_Central:1845 (DrugCentral)
- PMID:24306419 (Europe PMC)
- PDB:1Q0Y
- Reaxys:93704 (Reaxys)
3_STAR
(5R,6S,9R,13S,14R)-4,5-epoxy-N-methyl-7-morphinen-3,6-diol
morphinum
morfina
Morphia
(5alpha,6alpha)-didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol
(-)-morphine
(7R,7AS,12BS)-3-METHYL-2,3,4,4A,7,7A-HEXAHYDRO-1H-4,12-METHANO[1]BENZOFURO[3,2-E]ISOQUINOLINE-7,9-DIOL
(5alpha,6alpha)-17-methyl-7,8-didehydro-4,5-epoxymorphinan-3,6-diol
Morphin
morphium
InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1
Term relations
- tertiary amino compound
- organic heteropentacyclic compound
- morphinane alkaloid
- has role some vasodilator agent
- has role some xenobiotic
- has role some drug allergen
- has role some opioid analgesic
- is conjugate base of some morphine(1+)
- has role some environmental contaminant
- has role some anaesthetic
- has role some mu-opioid receptor agonist
- has parent hydride some morphinan
- has role some plant metabolite
- has role some geroprotector