autosomal dominant complex spastic paraplegia
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MONDO_0015087 |
[Autosomal dominant form of complex hereditary spastic paraplegia.] |
corneal dystrophy, punctiform and polychromatic pre-descemet
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MONDO_0859248 |
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frontotemporal dementia
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MONDO_0017276 |
[Frontotemporal dementia (FTD) comprises a group of neurodegenerative disorders, characterized by progressive changes in behavior, executive dysfunction and language impairment, as a result of degeneration of the medial prefrontal and frontoinsular cortices. Four clinical subtypes have been identified: semantic dementia, progressive non-fluent aphasia, behavioral variant FTD and right temporal lobar atrophy.] |
leukodystrophy, hypomyelinating, 24
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MONDO_0859242 |
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spinocerebellar ataxia, autosomal recessive 32
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MONDO_0859245 |
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autosomal recessive cerebellar ataxia
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MONDO_0015244 |
[Autosomal recessive cerebellar ataxias (ARCA) are a heterogeneous group of rare neurological disorders involving both the central and peripheral nervous system (and in some cases other systems and organs), and characterized by degeneration or abnormal development of the cerebellum and spinal cord and, in most cases, early onset occurring before the age of 20 years.] |
ischemic disease
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MONDO_0005053 |
[Lack of blood supply to an area of the body, resulting in impairment of tissue oxygenation.] |
osteoporosis
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MONDO_0005298 |
[A condition of reduced bone mass, with decreased cortical thickness and a decrease in the number and size of the trabeculae of cancellous bone (but normal chemical composition), resulting in increased fracture incidence. Osteoporosis is classified as primary (Type 1, postmenopausal osteoporosis; Type 2, age-associated osteoporosis; and idiopathic, which can affect juveniles, premenopausal women, and middle-aged men) and secondary osteoporosis (which results from an identifiable cause of bone mass loss).] |
metabolic bone disorder
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MONDO_0800486 |
[A group of disorders that affect the bones secondary to increased levels of minerals or deficient levels of minerals such as calcium, magnesium, phosphorus, and vitamin D. Representative examples are osteomalacia, osteoporosis, and Paget disease.] |
osteogenesis imperfecta and a reduction of bone mineral density.
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MONDO_0800064 |
[A skeletal dysplasia characterized by osteogenesis imperfecta and decreased bone density.] |
bone resorption disease
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MONDO_0000837 |
[A disease that has its basis in the disruption of bone resorption. Bone resorption is a process in which specialized cells known as osteoclasts degrade the organic and inorganic portions of bone, and endocytose and transport the degradation products.] |
peripheral vascular disease
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MONDO_0005294 |
[Any disorder affecting blood flow through the veins or arteries outside of the heart.] |
cluster headache syndrome
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MONDO_0043537 |
[A headache disorder that is characterized by periodic severe, unilateral orbital, supraorbital, and/or temporal pain, and is associated with ipsilateral cranial autonomic symptoms.] |
trigeminal autonomic cephalalgia
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MONDO_0015530 |
[A headache disorder characterized by episodes of unilateral, short lasting pain and associated ipsilateral cranial autonomic symptoms.] |
fetal lung interstitial tumor
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MONDO_0017289 |
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pleuropulmonary blastoma
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MONDO_0011014 |
[A malignant neoplasm affecting the lungs and/or the pleura. Pleuropulmonary blastoma is seen in children. Microscopically, the tumor may show features of chondrosarcoma, leiomyosarcoma, rhabdomyosarcoma, liposarcoma, or undifferentiated sarcoma. In approximately 25% of patients with pleuropulmonary blastoma, there are other lesions or neoplasms that may affect patients or their families, including lung or kidney cysts, and ovarian or testicular neoplasms. Heterozygous germline mutations in DICER1 gene have been identified in families harboring pleuropulmonary blastomas.] |
Xp22.13p22.2 duplication syndrome
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MONDO_0017284 |
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partial duplication of the short arm of chromosome X
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MONDO_0017009 |
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auditory neuropathy, autosomal dominant 3
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MONDO_0859235 |
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auditory neuropathy
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MONDO_0021944 |
[A hearing disorder characterized by impaired transmission of signals through the auditory nerve, resulting in mild to severe hearing loss and poor speech perception.] |