A rare, systemic amyloidosis characterized by slowly progressive renal disease presenting with proteinuria, hypertension and decreased glomerular filtration rate leading to progressive renal failure. Histology reveals amyloid deposits of leukocyte chemotactic factor-2 protein in the renal cortical interstitium, tubular basement membranes, glomeruli and the vessel walls. Extra-renal deposits can be seen in the liver, lungs, spleen and adrenal glands. [ Orphanet:439224 ]
Synonyms: LECT2 amyloidosis leukocyte chemotactic factor-2 amyloidosis
Term information
- MEDGEN:1801621 (MONDO:equivalentTo)
- Orphanet:439224 (MONDO:equivalentTo)
- UMLS:C5680047 (MONDO:equivalentTo)
- GARD:21827 (MONDO:GARD)
gard_rare, ordo_disorder, otar, rare, nord_rare, orphanet_rare
http://linkedlifedata.com/resource/umls/id/C5680047
http://identifiers.org/medgen/1801621
http://www.orpha.net/ORDO/Orphanet_439224