Acute monoblastic leukemia (AML-M5), is one of the most common subtypes of acute myeloid leukemia (AML) that is either comprised of more than 80% of monoblasts (AML-M5a) or 30-80% monoblasts with (pro)monocytic differentiation (AML-M5b). AML-M5 presents with asthenia, pallor, fever, and dizziness. Specific features of AML-M5 include hyperleukocytosis, propensity for extramedullary infiltrates, coagulation abnormalities including disseminated intravascular coagulation and neurological disorders. Leukemia cutis and gingival infiltration can also be seen. A characteristic translocation observed in AML-M5 is t(9;11). [ Orphanet:514 ]

Synonyms: leukemia, monocytic, malignant AML M5 acute monocytic leukemia, morphology (morphologic abnormality) acute monoblastic leukaemia and acute monocytic leukaemia acute monocytic leukemia (FAB M5B) acute monocytic leukemia (FAB M5b) acute monocytic leukemia acute monocytic leukemia, FAB M5 acute monocytic leukaemia without mention of remission acute monoblastic leukemia and acute monocytic leukemia acute monocytic leukemia, morphology acute monocytic leukaemia (FAB M5b) acute monocytic leukaemia (FAB M5B) monocytic leukemia, acute acute monocytic leukemia without mention of remission

This is just here as a test because I lose it

Term information

database cross reference
  • EFO:0000221 (MONDO:equivalentTo)
  • ONCOTREE:AMOL (MONDO:equivalentTo)
  • MESH:D007948 (Orphanet:514/e)
  • CSP:2004-2820 (DOID:8864)
  • icd11.foundation:517546180 (https://orcid.org/0000-0002-4142-7153)
  • OMIM:151380 (MONDO:equivalentTo)
  • DOID:8864 (MONDO:equivalentTo)
  • SCTID:413441006 (MONDO:equivalentTo)
  • MEDGEN:7319 (MONDO:equivalentTo)
  • ICD9:206.0 (EFO:0000221)
  • MedDRA:10000871 (Orphanet:514/e)
  • MedDRA:10059439 (Orphanet:514/e)
  • GARD:525 (MONDO:GARD)
  • NANDO:2200009 (https://orcid.org/0000-0003-0011-764X)
  • NANDO:2200008 (https://orcid.org/0000-0003-0011-764X)
  • ICDO:9891/3 (NCIT:C4861)
  • NCIT:C4861 (MONDO:equivalentTo)
  • Orphanet:514 (MONDO:equivalentTo)
  • UMLS:C0023465 (MONDO:equivalentTo)
Subsets

ordo_disorder, gard_rare, otar, rare, nord_rare, orphanet_rare

closeMatch

http://identifiers.org/meddra/10059439

http://identifiers.org/meddra/10000871

exactMatch

http://identifiers.org/snomedct/413441006

http://purl.obolibrary.org/obo/NCIT_C4861

http://www.orpha.net/ORDO/Orphanet_514

http://purl.obolibrary.org/obo/DOID_8864

http://identifiers.org/medgen/7319

https://omim.org/entry/151380

http://identifiers.org/mesh/D007948

http://linkedlifedata.com/resource/umls/id/C0023465

excluded subClassOf

http://purl.obolibrary.org/obo/MONDO_0011118

has broad synonym

monocytic leukaemia

monocytic leukemia

has related synonym

leukemia, acute monocytic

acute monoblastic leukaemia

acute monoblastic/monocytic leukaemia

acute myeloblastic leukemia type 5

acute myeloblastic leukaemia type 5

acute monoblastic/monocytic leukemia

AML-M5

acute monoblastic leukemia

id

MONDO:0007896

seeAlso

https://rarediseases.info.nih.gov/diseases/525/acute-monoblastic-leukemia

Term relations