Keratolytic winter erythema is a rare epidermal disease, characterized by recurrent centrifugal palmoplantar peeling and erythema presenting seasonal variation (cold weather). Skin lesions may spread to the dorsum of hands and feet and to the interdigital spaces. Lower legs, knees and thighs may also be involved. Episodes may be preceded by itch and hyperhidrosis. Skin biopsy reveals an epidermal spongiosis with clefting in the stratum corneum, followed by regrowth. Keratolytic winter erythema follows an autosomal dominant mode of transmission. [ Orphanet:50943 ]
Synonyms: keratolytic winter erythema Erythrokeratolysis hiemalis Oudtshoorn disease
Term information
- ICD9:695.89 (MONDO:relatedTo)
- MESH:C536155 (Orphanet:50943/e)
- Orphanet:50943 (OMIM:148370)
- NORD:1286 (MONDO:NORD)
- MEDGEN:98359 (MONDO:equivalentTo)
- GARD:8275 (MONDO:GARD)
- OMIM:148370 (Orphanet:50943/e)
- SCTID:239064000 (MONDO:equivalentTo)
- UMLS:C0406756 (MONDO:equivalentTo)
gard_rare, ordo_disorder, otar, rare, nord_rare, orphanet_rare
http://identifiers.org/mesh/C536155
http://identifiers.org/snomedct/239064000
http://linkedlifedata.com/resource/umls/id/C0406756
http://www.orpha.net/ORDO/Orphanet_50943
http://identifiers.org/medgen/98359
https://omim.org/entry/148370
Oudtshoorn skin
Erythrokeratolysis hiemalis ichthyosis
keratolytic WINTER erythema
KWE
Oudtshoorn skin disease