An unusual benign or malignant neoplasm characterized by the presence of neoplastic large polygonal cells with granular, eosinophilic cytoplasm which contains abundant lysosomes. It was originally thought to be a tumor originating from muscle cells and was named granular cell myoblastoma. Subsequent studies have suggested a derivation from Schwann cells. It affects females more often than males and it usually presents as a solitary mass. A minority of patients have multiple tumors. It can arise from many anatomic sites including the posterior pituitary gland, skin, oral cavity, esophagus, stomach, heart, mediastinum, and breast. [ NCIT:C3474 ]

Synonyms: granular cell myoblastoma granular cell tumour (morphologic abnormality) Abrikossoff's tumor granular cell neoplasm granular cell tumor (morphologic abnormality) granular cell nerve sheath tumour Abrikossoff's tumour granular cell tumor Abrikossoff tumor granular cell schwannoma granular cell nerve sheath tumor Abrikossoff tumour

This is just here as a test because I lose it

Term information

database cross reference
  • MESH:D016586 (MONDO:equivalentTo)
  • MESH:C535558 (MONDO:equivalentTo)
  • ICDO:9580/0 (NCIT:C3474)
  • ICD9:215.9 (MONDO:relatedTo)
  • GARD:9618 (MONDO:GARD)
  • NCIT:C3474 (MONDO:exact-label-match)
  • EFO:1000284 (MONDO:equivalentTo)
  • SCTID:404035005 (MONDO:equivalentTo)
  • DOID:2411 (MONDO:equivalentTo)
  • UMLS:C0085167 (MONDO:equivalentTo)
  • ONCOTREE:GCT (MONDO:equivalentTo)
  • MEDGEN:88345 (MONDO:equivalentTo)
Subsets

gard_rare, otar, rare, nord_rare

comment

Editor note: MESH considers this a myoblastoma but we go with NCIT which states nerve sheath origin, consistent with GARD definition; also check ONCOTREE placement

exactMatch

http://identifiers.org/mesh/C535558

http://linkedlifedata.com/resource/umls/id/C0085167

http://purl.obolibrary.org/obo/NCIT_C3474

http://identifiers.org/mesh/D016586

http://purl.obolibrary.org/obo/DOID_2411

http://identifiers.org/medgen/88345

http://identifiers.org/snomedct/404035005

has narrow synonym

neoplasm of granular cell

granular cell tumour NOS (morphologic abnormality)

granular cell tumor NOS (morphologic abnormality)

has related synonym

Abrikosoff's granulous cell tumor

Abrikosov’s tumour

Abrikosov's tumor

Abrikosoff's tumor

Abrikosoff's granulous cell tumour

Abrikosov’s tumor

giant granulocellular Abrikosov's tumour

malignant variant of Abrikosov's tumor

giant granulocellular Abrikosov's tumor

Abrikosoff's tumour

GCT

malignant variant of Abrikosov's tumour

Abrikosov's tumour

id

MONDO:0006235

seeAlso

https://rarediseases.info.nih.gov/diseases/9618/granular-cell-tumor

Term relations

Subclass of: