An aggressive malignant tumor arising from trophoblastic cells. The vast majority of cases arise in the uterus and represent gestational choriocarcinomas that derive from placental trophoblastic cells. Approximately half of the cases develop from a complete hydatidiform mole. A minority of cases arise in the testis or the ovaries. There is often marked elevation of human chorionic gonadotropin (hCG) in the blood. Choriocarcinomas disseminate rapidly through the hematogenous route; the lungs are most frequently affected. [ NCIT:C2948 ]
Synonyms: chorion carcinoma choriocarcinoma (disease) chorioblastoma chorionic carcinoma chorioepithelioma choriocarcinoma, malignant choriocarcinoma
Term information
- GARD:6059 (MONDO:GARD)
- ICDO:9100/3 (NCIT:C2948)
- DOID:3594 (MONDO:equivalentTo)
- HP:0100768 (MONDO:otherHierarchy)
- NANDO:2200070 (https://orcid.org/0000-0003-0011-764X)
- MESH:D002822 (MONDO:equivalentTo)
- MEDGEN:40278 (MONDO:equivalentTo)
- ONCOTREE:BCCA (MONDO:equivalentTo)
- UMLS:C0008497 (MONDO:equivalentTo)
- NCIT:C2948 (MONDO:equivalentTo)
- SCTID:188188009 (MONDO:equivalentTo)
- EFO:0002893 (MONDO:equivalentTo)
gard_rare, otar, rare, nord_rare
http://purl.obolibrary.org/obo/NCIT_C2948
http://identifiers.org/medgen/40278
http://purl.obolibrary.org/obo/DOID_3594
http://identifiers.org/mesh/D002822
http://linkedlifedata.com/resource/umls/id/C0008497
http://identifiers.org/snomedct/188188009
http://purl.obolibrary.org/obo/MONDO_0002178
http://purl.obolibrary.org/obo/MONDO_0004970