A neuroendocrine carcinoma arising from the C-cells of the thyroid gland. It is closely associated with multiple endocrine neoplasia syndromes. Approximately 10% to 20% of medullary thyroid carcinomas are familial. Patients usually present with a thyroid nodule that is painless and firm. In the majority of cases nodal involvement is present at diagnosis. Surgery is the preferred treatment for both primary lesions and recurrences. This carcinoma is generally not very sensitive to radiation and almost unresponsive to chemotherapy. [ NCIT:C3879 ]

Synonyms: parafollicular cell carcinoma medullary carcinoma of thyroid gland C cell carcinoma thyroid gland medullary carcinoma medullary carcinoma ultimobranchial thyroid tumor medullary carcinoma of the thyroid gland carcinoma of parafollicular cell thyroid medullary carcinoma thyroid gland medullary cancer medullary thyroid gland carcinoma thyroid gland neuroendocrine carcinoma medullary thyroid cancer carcinoma, C-cell, malignant medullary carcinoma of thyroid medullary carcinoma of the thyroid medullary thyroid carcinoma MTC ultimobranchial thyroid tumour

This is just here as a test because I lose it

Term information

database cross reference
  • Orphanet:1332 (MONDO:equivalentTo)
  • MedDRA:10027101 (Orphanet:1332/e)
  • SCTID:255032005 (MONDO:equivalentTo)
  • icd11.foundation:578519098 (https://orcid.org/0000-0002-4142-7153)
  • DOID:3973 (MONDO:equivalentTo)
  • ONCOTREE:THME (MONDO:equivalentTo)
  • UMLS:C0238462 (MONDO:equivalentTo)
  • MEDGEN:66772 (MONDO:equivalentTo)
  • NCIT:C3879 (MONDO:equivalentTo)
  • GARD:7004 (MONDO:GARD)
  • HP:0002865 (MONDO:otherHierarchy)
  • NANDO:2201054 (https://orcid.org/0000-0003-0011-764X)
Subsets

gard_rare, ordo_disorder, matrix_llm__is_cancer_other, matrix_txgnn_grouping_cancer_or_benign_tumor, matrix_llm__is_glucose_dysfunction_other, otar, matrix_llm__tag_qualy_lost_other, matrix_llm__txgnn_other, matrix_llm__medical_specialization_other, mondo_top_grouping_member, harrisons_view_endocrine_system_disorder, mondo_top_grouping_endocrine_system_disorder, matrix_txgnn_grouping_endocrine_system_disorder, matrix_included, matrix_llm__tag_existing_treatment_other, matrix_llm__anatomical_other, matrix_llm__is_pathogen_caused_other, mondo_top_grouping_cancer_or_benign_tumor, matrix_txgnn_grouping_member, harrisons_view_cancer_or_benign_tumor, rare, harrisons_view_member, orphanet_rare

abbreviation
THME [ ONCOTREE:THME ]

UK spelling synonym
ultimobranchial thyroid tumour [ DOID:3973 ]

abbreviation
MTC [ NCIT:C3879 Orphanet:1332 ]

closeMatch

http://identifiers.org/meddra/10027101

conformsTo

http://purl.obolibrary.org/obo/mondo/patterns/carcinoma.yaml

exactMatch

http://linkedlifedata.com/resource/umls/id/C0238462

http://purl.obolibrary.org/obo/mondo/sources/icd11foundation/578519098

http://identifiers.org/medgen/66772

http://purl.obolibrary.org/obo/DOID_3973

http://www.orpha.net/ORDO/Orphanet_1332

http://identifiers.org/snomedct/255032005

http://purl.obolibrary.org/obo/NCIT_C3879

has related synonym

thyroid carcinoma, medullary

thyroid cancer, medullary

THME

medullary thyroid cancer (MTC)

id

MONDO:0015277