A condition that develops in people who do not consume an adequate amount of vitamin C in their diet. Although scurvy is relatively rare in the United States, it continues to be a problem in malnourished populations around the world (such as impoverished, underdeveloped third world countries). Early features of the condition include general weakness, fatigue and aching limbs. If left untreated, more serious problems can develop such as anemia, gum disease, and skin hemorrhages. Symptoms generally develop after at least 3 months of severe or total vitamin C deficiency. Scurvy can be cured with vitamin C supplements taken by mouth. Once recovery is complete, dietary modifications to ensure the 'recommended daily intake' of vitamin C is reached will prevent relapse. Except in the case of severe dental disease, permanent damage from scurvy does not usually occur. [ https://rarediseases.info.nih.gov/diseases/10406/scurvy ]
Synonyms: ascorbic acid deficiency scurvy deficiency of vitamin C vitamin C deficiency
Term information
- MESH:D001206 (MONDO:equivalentTo)
- MESH:D012614 (MONDO:equivalentTo)
- SCTID:76169001 (MONDO:equivalentTo)
- DOID:13724 (MONDO:equivalentTo)
- MedDRA:10047623 (EFO:1000822)
- ICD9:267 (MONDO:i2s)
- MEDGEN:20684 (MONDO:equivalentTo)
- UMLS:C0036474 (MONDO:equivalentTo)
- OMIM:240400 (MONDO:equivalentTo)
- MedDRA:10039768 (EFO:1001169)
- NCIT:C35010 (MONDO:equivalentTo)
- DOID:13577 (MONDO:equivalentObsolete)
- ICD10CM:E54 (MONDO:equivalentTo)
- icd11.foundation:708602629 (MONDO:equivalentTo)
- EFO:1001169 (MONDO:equivalentTo)
matrix_llm__is_cancer_other, matrix_llm__is_glucose_dysfunction_other, otar, matrix_llm__tag_qualy_lost_other, matrix_llm__medical_specialization_other, matrix_llm__txgnn_other, mondo_top_grouping_member, mondo_top_grouping_nutritional_disorder, matrix_included, matrix_llm__tag_existing_treatment_other, matrix_llm__anatomical_other, harrisons_view_nutritional_disorder, matrix_llm__is_pathogen_caused_other, mondo_top_grouping_metabolic_disease, matrix_txgnn_grouping_metabolic_disease, matrix_txgnn_grouping_member, harrisons_view_member, harrisons_view_metabolic_disease
An argument can be made that Vitamin C deficiency is a genetic disease shared by all humans, due to our loss of the GULO gene. See OMIM for discussion. Here we choose not to treat as genetic.
http://linkedlifedata.com/resource/umls/id/C0036474
http://identifiers.org/medgen/20684
http://identifiers.org/mesh/D012614
http://purl.obolibrary.org/obo/mondo/sources/icd11foundation/708602629
http://www.ebi.ac.uk/efo/EFO_1001169
http://purl.obolibrary.org/obo/DOID_13724
http://identifiers.org/snomedct/76169001
http://identifiers.org/mesh/D001206
https://omim.org/entry/240400
http://purl.obolibrary.org/obo/NCIT_C35010
http://purl.bioontology.org/ontology/ICD10CM/E54
vitamin C, inability to synthesize
L-gulonolactone oxidase pseudogene
scorbutus
L-gulonolactone oxidase, nonfunctional
vitamin C, inability to synthesise
Gulo, nonfunctional
hypoascorbemia