A parasitic disorder caused by protozoa of the Trypanosoma brucei species. It is transmitted by flies and is endemic in various regions of Sub-Saharan Africa. Signs and symptoms include fever, joint pain, headache, and significant swelling of the lymph nodes. If left untreated, the parasitic infection causes anemia, heart, kidney, and endocrine failure, and neurologic damage. Subsequently patients develop confusion, disruption of the sleep cycle, and mental deterioration. The infection may lead to coma and death. [ NCIT:P378 ]
Synonyms: Africam sleeping sickness African sleeping sickness African trypanosomiasis sleeping sickness
Term information
- MESH:D014353 (Orphanet:3385/e)
- MedDRA:10001461 (Orphanet:3385/e)
- Orphanet:3385 (MONDO:equivalentTo)
- EFO:0005225 (MONDO:equivalentTo)
- ICD9:086.5 (MONDO:i2s)
- SCTID:27031003 (MONDO:equivalentTo)
- DOID:10112 (MONDO:equivalentTo)
- NCIT:C84541 (MONDO:equivalentTo)
- GARD:7826 (MONDO:GARD)
- UMLS:C0041228 (MONDO:equivalentTo)
- MEDGEN:21714 (MONDO:equivalentTo)
gard_rare, harrisons_view_infectious_disease, ordo_disorder, matrix_llm__is_cancer_other, matrix_llm__is_glucose_dysfunction_other, otar, matrix_llm__tag_qualy_lost_other, matrix_llm__txgnn_other, matrix_llm__medical_specialization_other, mondo_top_grouping_member, nord_rare, matrix_included, matrix_llm__tag_existing_treatment_other, mondo_top_grouping_infectious_disease, matrix_llm__anatomical_other, matrix_llm__is_pathogen_caused_other, matrix_txgnn_grouping_member, matrix_txgnn_grouping_infectious_disease, rare, harrisons_view_member, orphanet_rare
http://linkedlifedata.com/resource/umls/id/C0041228
http://www.orpha.net/ORDO/Orphanet_3385
http://identifiers.org/snomedct/27031003
http://www.ebi.ac.uk/efo/EFO_0005225
http://identifiers.org/medgen/21714
http://purl.obolibrary.org/obo/DOID_10112
http://purl.obolibrary.org/obo/NCIT_C84541